<<
>>

. G

/ - pH (Bainton et al., 1971; Spitznagel et al., 1974; Olsson, 1977; Havemann, Gramse, 1984; Baggiolini, Dewald, 1985).

- (Olsson, 1977; Olsson et al., 1978) (Starkey, Barrett, 1976; Barrett, 1981). , - , 34 , (1~11) (Olsson, 1977). G (. 23) (Salvesen et al., 1987).

(1314 %) (1920 %), . . , , 25 00029 500 . (, ) pH 7.07.5.

(-, - , - .

- , , , G (Starkey, Barrett, 1976), .

G ( 3.4.21.20) , , (1, , 4, 5), . (Havemann, Gramse, 1984; , , 1985) . G - (Odeberg, Olsson, 1976; Olsson et al., 1978), (Drazin, Lehrer, 1977).

: : G: 11VGGRKARPRQFPFLASIQNQGR------ H-FCGGALIHARFVMTAASCFQSQNPGVSTWL

' IVGGRRARPHAWPFMVSLQLRG- -G-H-FCGATLIAPNFVMSAAHCVANVNVRAVRWL IIGGRESRPHSRPYMAYLQIQSPAGQSR-CGGFLVREDFVLTAAHCWGS----------- NINVTL

: : G: GAYDLRRR-ERQSRQTFSISS-MSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPL

GAHNLSRR-EP-TRQVFAVQR-IFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPA

GAHNIQRR-EN-TQQHITARRAIRHPQYNQRTIQNDIMLLQLSRRVRRNRNVNPVALPR

: : G: QNATVEA-GTRCQVA-GWGSQRSGGRLSRFPRFVNVTVTPEDQCRPNN----------------- VC

QGRRLGN-GVQC-LAMGWGLLGRNRGIASVLQELNVTWTSL-CRRSN------------------- VC

AQEGLRP-GTLCTVA-GWGRVS-MRRGTDTLREVQLRVQRDRQCLRIFGSYDPRR-QIC

: : G: TGVLTRRG-GICNGDGGTPLVCEGLAHGVASFSLGPC-GRG-PDFFTRVALFRDWIDG TFVRG-RQAGVCFGDSGSPLVCNGLIHGIASFVR-GGCASGLYPDAFAPVAQFNMWIDS VGDRRERKAAF-KGDSGGPLLCNNVAHGIVSYGKSSG--------- VPPEVFTRVSSFLPWIRT
: : G: VLNNPG -G2 2 5 IIQ218

TMRSFKLLDQMETPL235

6 . .

.
23. .

(, D, S), - - G. , ,

.

, 10 5070 .

-, G - , . . NaCl, 0.2 , . , G , . , S. aureus . coli . , - , , G.

-, . - .

-, , () , . , 10-6 90 % S. aureus , . coli 2.5 X 10_6 .

-, G , -, - . , G , - . , , .

<< | >>
: . .. . .: ,2006.261 .. 2006

. G:

  1. , ,
  2. 1.2.1.
  3. . , 2002. 111 ., 2002
  4. 1
  5. 2
  6. 2.1. -
  7. 2.2. -
  8. 2.3.
  9. 2.4.
  10. 2.5.  
  11. 2.6.  
  12. 2.7.  
  13. 2.8.  
  14. 2.9.  
  15. 3
- - -
- - - - - - - - - - - - - -