<<
>>

.., ., . // , - 1972, 22.578-580.

., , // , - 1956, 51(15), - .641-645.

., . // - 1954, 4, - .201-208.

.., .. , - . - , ., 2008, 956 .

. ., . ., . ., . . . 2461 17 2008 .

.., .., .., .., .. , 2010

.., .., .., .., .., .., .., ..■ .. - . , 2011, 7, . 16-21.

. , //, - 1956, - 1(4), - . 7-10

. , (27.03.2008, www.regmed.ru).



.., .., .., .., .., - - . , 2010.

, , , , , . . ., 2002, 219.

.. , , 2008, 967

. // - 1935, 11, . 1689

., ., , //, 1953, - 1(1), - . 6-11.

Agarwal K, Jones DE, DalyAK, James OF, Vaidya B, Pearce S, Bassendine MF. CTLA-4 gene polymorphism confers susceptibility to primary biliary cirrhosis. J Hepatol. 2000;32(4):538-541.

Aller R, De Luis DA, Fernandez L, Calle F, Velayos B, Izaola O, Gonzalez Sagrado M, Conde R, Gonzalez JM. Influence of Ala54Thr polymorphism of fatty acid-binding protein 2 on histological alterations and insulin resistance of non alcoholic fatty liver disease. Eur Rev Med Pharmacol Sci. 2009;13(5):357-364.

Andrade RJ, Robles M, Ulzurrun E, Lucena MI. Drug-induced liver injury: insights from genetic studies. Pharmacogenomics. 2009;10(9):1467-1487.

Banerjee RV, Matthews RG. Cobalamin-dependent methionine synthase. FASEB J. 1990;4(5):1450-1459.

Bauman W, Kunkel H. [Therapy of liver cirrhosis with special reference to out observations on therapy with prohepar.]. Arztl Wochensch. 1953 Mar 13;8(11):257-60.

Beadling C, Smith KA. DNA array analysis of interleukin-2-regulated imme- diate/early genes. Med Immunol. 2002;1(1):2.

Boselli A. [A new hepatoprotective preparation. Biochemical aspects and clinical studies] Clin Ter. 1968;44(2):115-156.

BOULANGER P, BISERTE G, PLAQUET-SCHOONAERT T. [The free and combined amino acid compositon of liver extracts used therapeutically.] Therapie. 1959;14:1000-1006.

Brind AM, Hurlstone A, Edrisinghe D, Gilmore I, Fisher N, Pirmohamed M, Fryer AA. The role of polymorphisms of glutathione S-transferases GSTM1, M3, P1, T1 and A1 in susceptibility to alcoholic liver disease. Alcohol Alcohol. 2004;39(6):478-483.

Chiba T, Horiuchi M, Koike F. [Effect of thiol compounds on experimental liver damage (IV). Detoxicating effect of tiopronin, glutathione and cysteine on ethionine induced lived damage (authors transl)] Nippon Yakurigaku Zasshi. 1979;75(7):645-654.

DE PAULIS D, ROSSI L. [Characterization of vitamin B 12 in liver extracts.] Boll Chim Farm. 1961;100:2-8.

Erraji-Benchekroun L, Couton D, Postic C, Borde I, Gaston J, Guillet JG, Andre C. Overexpression of beta2-adrenergic receptors in mouse liver alters the expression of gluconeogenic and glycolytic enzymes. Am J Physiol Endocrinol Metab. 2005;288(4):E715-22 Epub 2004 D.

Estrela JM, Saez GT, Such L, Vina J. The effect of cysteine and N- acetyl cysteine on rat liver glutathione (GSH). Biochem Pharmacol. 1983;32(22):3483-3485.

Fanelli V. [Clinical observations on a new preparation with hepatoprotective action] Clin Ter. 1967;40(2):145-156.

Friederici L. [Effect of purines, prohepar, hepanovin and nucleotrat on bone marrow cultures.] Naunyn Schmiedebergs Arch Exp Pathol Pharmakol. 1956;229(2):171-81.

Fujisawa A. Leber Galle Bauchspeichedruse, - 1981, 4, - P.801.

Geerts A. History, heterogeneity, developmental biology, and functions of quiescent hepatic stellate cells. // Semin Liver Dis. - 2001, - 21(3), - P. 311-335.

Ghobadloo SM, Yaghmaei B, Bakayev V, Goudarzi H, Noorinayer B, Rad FH, Samiy S, Aghabozorghi S, Zali MR. GSTP1, GSTM1, and GSTT1 genetic polymorphisms in patients with cryptogenic liver cirrhosis. J Gastrointest Surg. 2004;8(4):423-427.

GIURGEA M, STERESCU M, HARAGRA S, TROPA V. [The spectrophotomet- ric determination of vitamin B 12 in ampules and concentrated liver extracts.] Pharmazie. 1959;14:394-396.

Gohr H, Gorges T. [Clinical studies on the therapeutic effect of the liver hydrolysate prohepar in the therapy of liver diseases under control of functional disorders in protein and bile pigment metabolism.]. Z Gesamte Inn Med. 1953 Dec 1;8(23):1073-7.

Gomez Ponsa JM. [1st experiences with the use of a new liver protector in liver diseases] Rev Esp Enferm Apar Dig. 1970;32(5):593-600.

Grove J, Daly AK, Bassendine MF, Gilvarry E, Day CP. Interleukin 10 promoter region polymorphisms and susceptibility to advanced alcoholic liver disease. Gut. 2000;46(4):540-545.

Hasan SH, Kotaki A, Yagi K. Studies on myoinositol. VI. Effect of myoinositol on plasma lipoprotein metabolism of rats suffering from fatty liver. J Vitaminol (Kyoto). 1970;16(2):144-148.

Hasan SH, Nakagawa Y, Nishigaki I, Yagi K. Studies on myoinositol. 8. The incorporation of 3 H-myoinositol into phosphatidyl-inositol of fatty liver. J Vitaminol (Kyoto). 1971;17(3):159-162.

Hasan SH, Nishigaki I, Tsutsui Y, Yagi K. Studies on myoinositol. IX. Morphological examinaiton of the effect of massive doses of myoinositol on the liver and kidney of rat. J Nutr Sci Vitaminol (Tokyo). 1974;20(1):55-58.

Herrmann A, Maurer H. [The effects of prohepar on radiation sickness.]. Med Klin (Munich). 1955 Jun 24;50(25):1058-63.

Higashi T, Tateishi N, Sakamoto Y. Liver glutathione as a reservoir of L- cysteine. Prog Clin Biol Res. 1983;125:419-434.

Hirayama S. et al. Nisshin Igaku, - 1958, 45,- P.528.

Horakova O, Kostir J, Horak F. [The hepatotropic effect of alpha-lipoic acid] Cesk Farm. 1967;16(3):129-133.

Hsieh HI, Chen PC, Wong RH, Wang JD, Yang PM, Cheng TJ. Effect of the CYP2E1 genotype on vinyl chloride monomer-induced liver fibrosis among polyvinyl chloride workers. Toxicology. 2007;239(1-2):34-44 Epub 2007 Jun.

Huang YS, Su WJ, Huang yH, Chen CY, Chang FY, Lin HC, Lee SD. Genetic polymorphisms of manganese superoxide dismutase, NAD(P)H:quinone oxidoreductase, glutathione S-transferase M1 and T1, and the susceptibility to drug-induced liver injury. J Hepatol. 2007;47(1):128-34 Epub 2007 Ma.

Huang YS, Chern HD, Wu JC, Chao Y, Huang YH, Chang FY, Lee SD. Polymorphism of the N-acetyltransferase 2 gene, red meat intake, and the susceptibility of hepatocellular carcinoma. Am J Gastroenterol. 2003;98(6):1417-1422.

Hui Y, Yu-Yuan L, Yu-Qiang N, Wei-Hong S, Yan-Lei D, Xiao-Bo L, Yong- Jian Z. Effect of peroxisome proliferator-activated receptors-gamma and co- activator-lalpha genetic polymorphisms on plasma adiponectin levels and susceptibility of non-alcoholic fatty liver disease in Chinese people. Liver Int. 2008;28(3):385-92 Epub 2007 No.

Hung TM, Chang SC, Yu WH, Wang YW, Huang C, Lu SC, Lee PH, Chang MF. A novel nonsynonymous variant of matrix metalloproteinase-7 confers risk of liver cirrhosis. Hepatology. 2009;50(4):1184-1193.

Hunter EA, Grimble RF. Cysteine and methionine supplementation modulate the effect of tumor necrosis factor alpha on protein synthesis, glutathione and zinc concentration of liver and lung in rats fed a low protein diet. J Nutr. 1994;124(12):2319-2328.

lanas O, Olinescu R, Badescu I, Simionescu L, Popovici D. The influence of selenium organicum upon the hepatic function of carbon tetrachloride poisoned rats. Rom J Intern Med. 1995;33(1 -2):113-120.

lasinovskii MA, Terletskaia TM, Bondarchuk AF. [Use of lipoic acid in complex therapy of patients with liver diseases] Vrach Delo. 1969;5:9-12.

Invernizzi P, Selmi C, Poli F, Frison S, Floreani A, Alvaro D, Almasio P, Ro- sina F, Marzioni M, Fabris L, Muratori L, Qi L, Seldin MF, Gershwin ME, Podda M. Human leukocyte antigen polymorphisms in Italian primary biliary cirrhosis: a multicenter study of 664 patients and 1992 healthy controls. Hepatology. 2008;48(6):1906-1912.

Iredale J.P. Cirrhosis: new research provides a basis for rational and targeted treatments//BMJ - 2003, 327(7407) - P. 143-147.

Isoda K, Kagaya N, Akamatsu S, Hayashi S, Tamesada M, Watanabe A, Kobayashi M, Tagawa Y, Kondoh M, Kawase M, Yagi K. Hepatoprotective effect of vitamin B12 on dimethylnitrosamine-induced liver injury. Biol Pharm Bull. 2008;31(2):309-311.

Issekutz L. [Evaluation of the therapeutic effect of live protective substances] Arzneimittelforschun 1967;17(4):419-424.

Ivkov VG. [Lipoic (thioctic) acid and its significance in hepatology] Sov Med. 1969;32(10):122-128.

Iwamoto N, Ogawa Y, Kajihara S, Hisatomi A, Yasutake T, Yoshimura T, Mizuta T, Hara T, Ozaki I, Yamamoto K. Gln27Glu beta2-adrenergic receptor variant is associated with hypertriglyceridemia and the development of fatty liver. Clin Chim Acta. 2001;314(1-2):85-91.

Jelikic-StankovM, Uskokovic-Markovic S, Holclajtner-AntunovicI, Todorovic M, Djurdjevic P. Compounds of Mo, V and W in biochemistry and their biomedical activity. J Trace Elem Med Biol. 2007;21(1):8-16 Epub 2007 Jan.

Jones JR, Barrick C, Kim KA, Lindner J, Blondeau B, Fujimoto Y, Shiota M, Kesterson RA, Kahn BB, Magnuson MA. Deletion of PPARgamma in adipose tissues of mice protects against high fat diet-induced obesity and insulin resistance. Proc Natl Acad Sci U S A. 2005;102(17):6207-12 Epub 2005A.

Kabadi UM. Inhibition of glucagon secretion by crude liver extract in conscious dogs. Diabetes Res. 1993;23(1):41-46.

Kaczmarek M, Timofeeva OA, Karaczyn A, Malyguine A, Kasprzak KS, Salnikow K. The role of ascorbate in the modulation of HIF-lalpha protein and HIF-dependent transcription by chromium(VI) and nickel(II). Free Radic Biol Med. 2007;42(8):1246-57.

Kawaratani H, Tsujimoto T, Kitazawa T, Kitade M, Yoshiji H, Uemura M, Fukui H. Innate immune reactivity of the liver in rats fed a choline-deficient L-amino- acid-defined diet. World J Gastroenterol. 2008;14(43):6655-6661.

Kenney JL, Carlberg KA. The effect of choline and myo-inositol on liver and carcass fat levels in aerobically trained rats. Int J Sports Med. 1995;16(2):114-116.

KhanAJ, RuwaliM, ChoudhuriG, MathurN, HusainQ, ParmarD. Polymorphism in cytochrome P450 2E1 and interaction with other genetic risk factors and susceptibility to alcoholic liver cirrhosis. Mutat Res. 2009;664(1 -2):55-63 Epub 2009 Feb.

Kiemer AK, Mbller C, Vollmar AM.Inhibition of LPS-induced nitric oxide and TNF-alpha production by alpha-lipoic acid in rat Kupffer cells and in RAW264.7 murine macrophages. Immunol Cell Biol. 2002 Dec;80(6):550-7.

King CD, Rios GR, Green MD, Tephly TR. UDP-glucuronosyltransferases. Curr Drug Metab. 2000;1(2):143-161.

Koizumi B. et al. Klinische Medizin und Forschung, 1972, - 49, - P. 261.

Kotaki A, Sakurai T, Kobayashi M, Yagi K. Studies on myoinositol. IV. Effect of myoinositol on the cholesterol metabolism of rats suffering from experimental fatty liver. J Vitaminol (Kyoto). 1968;14(2):87-94.

Lazarus P, Zheng Y, Aaron Runkle E, Muscat JE, Wiener D. Genotype- phenotype correlation between the polymorphic UGT2B17 gene deletion and NNAL glucuronidation activities in human liver microsomes. Pharmacogenet Genomics. 2005;15(11):769-778.

Lin YC, Chang PF, Hu FC, Chang MH, Ni YH. Variants in the UGT1A1 gene and the risk of pediatric nonalcoholic fatty liver disease. Pediatrics. 2009;124(6): e1221-e1227.

Liu Y, Meng XW, Zhou LY, Zhang PY, Sun X, Zhang P. Genetic polymorphism and mRNA levels of cytochrome P450IIE1 and glutathione S-transferase P1 in patients with alcoholic liver disease in different nationalities. Hepatobiliary Pancreat Dis Int. 2009;8(2):162-167.

Lorenzo A, Auguet T, Vidal F, Broch M, Olona M, Gutierrez C, Lopez- Dupla M, Sirvent JJ, Quer JC, Santos M, Richart C. Polymorphisms of alcohol- metabolizing enzymes and the risk for alcoholism and alcoholic liver disease in Caucasian Spanish women. Drug Alcohol Depend. 2006;84(2):195-200.

Lucena MI, Andrade RJ, Martinez C, Ulzurrun E, Garcia-Martin E, Borraz Y, Fernandez MC, Romero-Gomez M, Castiella A, Planas R, Costa J, Anzola S, Agundez JA. Glutathione S-transferase ml and t1 null genotypes increase susceptibility to idiosyncratic drug-induced liver injury. Hepatology. 2008;48(2):588-596.

Lucena MI, Andrade RJ, MartHnez C, Ulzurrun E, GarcHa-MartHn E, Borraz Y, Fernôndez MC, Romero-Gomez M, Castiella A, Planas R, Costa J, Anzola S, Aghndez JA; Spanish Group for the Study of Drug-Induced Liver Disease.Gluta- thione S-transferase ml and t1 null genotypes increase susceptibility to idiosyncratic drug-induced liver injury. Hepatology. 2008 Aug;48(2):588-96.



Lugo-BaruquiA, Munoz-Valle JF, Arevalo-Gallegos S, Armendariz-Borunda J. Role of angiotensin II in liver fibrosis-induced portal hypertension and therapeutic implications. Hepatol Res. 2010;40(1):95-104 Epub 2009 Se.

Marcos M, Pastor I, Gonzalez-Sarmiento R, Laso FJ. A functional polymorphism of the NFKB1 gene increases the risk for alcoholic liver cirrhosis in patients with alcohol dependence. Alcohol Clin Exp Res. 2009;33(11):1857-62 Epub 2009 A.

Marcos M, Pastor I, Gonzalez-Sarmiento R, Laso FJ. A new genetic variant involved in genetic susceptibility to alcoholic liver cirrhosis: -330T&gt;G polymorphism of the interleukin-2 gene. Eur J Gastroenterol Hepatol. 2008;20(9):855-859.

Mariotti F, Simbelie KL, Makarios-Lahham L, Acute ingestion of dietary proteins improves post-exercise liver glutathione in rats in a dose-dependent relationship with their cysteine content. J Nutr. 2004;134(1):128-131.

Mauer-Bosse D. [Liver supporting therapy with prohepar in carcinoma and occupational poisoning.]. Ther Ggw. 1955 Feb;94(2):65-6.

Maurer H, Ripeckyj M. [Studies on radiation-protection by the spleen and liver hydrolysates prohepar and hepasplene.] Munch Med Wochenschr. 1956 Sep 21;98(38):1279-81.

Maurer H. [Effects of prohepar on tolerance of ionizing radiations with special consideration of blood proteins, the peripheral blood picture and blood glutathione levels.]. Arch Ohren Nasen Kehlkopfheilkd. 1955;167(2-6):394-403.

Mikhail TH, Ibrahim KM, Awadallah R, Mona E. The effect of vitamin B12 on tetracycline-induced fatty liver. Z Ernahrungswiss. 1980;19(3):173-178.

Mitani S. et al, Leber Galle Bauchspeichedruse, - 1976, - 17, - P. 869.

Moller E, Brinkmann W, Weber O, Wildhirt E. [Treatment of chronic liver diseases with thioctic acid] Med Klin. 1967;62(10):380-384.

Moreno M, Ramalho LN, Sancho-Bru P, Ruiz-Ortega M, Ramalho F, Abrades JG, Colmenero J, Dominguez M, Egido J, Arroyo V, Gines P, Bataller R. Ator- vastatin attenuates angiotensin II-induced inflammatory actions in the liver. Am J Physiol Gastrointest Liver Physiol. 2009;296(2):G147-56 Epub 2008 D.

Moreno M, Gonzalo T, Kok RJ, Sancho-Bru P, van Beuge M, Swart J, Prakash J, Temming K, Fondevila C, Beljaars L, Lacombe M, van der Hoeven P, Arroyo V, Poelstra K, Brenner DA, Gines P, Bataller R. Reduction of advanced liver fibrosis by short-term targeted delivery of an angiotensin receptor blocker to hepatic stellate cells in rats. Hepatology. 2010;51(3):942-952.

Mu YP, Ogawa T, Kawada N. Reversibility of fibrosis, inflammation, and endoplasmic reticulum stress in the liver of rats fed a methionine-choline-deficient diet. Lab Invest. 2010;90(2):245-56 Epub 2009 No.

Mueller-Hepburn E. [Clinical experiences with unpurified liver extract (prohepar) in liver injury.]. Medizinische. 1953 Oct 10;41:1336-8.

Muller C, Dunschede F, Koch E, Vollmar AM, Kiemer AK. Alpha-lipoic acid preconditioning reduces ischemia-reperfusion injury of the rat liver via the PI3-kinase/Akt pathway. Am J Physiol Gastrointest Liver Physiol. 2003;285(4): G769-78.

MURABAYASHI A, YAMADA M. [EFFECTS OF THE ORAL ADMINISTRATION OF HEPATOPROTECTIVE DRUGS ON THE PREVENTION OF HEPATIC DISORDERS AFTER LUNG SURGERY.] Kyobu Geka. 1964;17:372-374.

Murata C, Watanabe T, Furuya H, Sugioka Y, Mikurube H, YokoyamaA, Atsumi Y, Matsuoka K, Okazaki I. Aldehyde dehydrogenase 2 and beta3-adrenergic receptor gene polymorphisms: their association with elevated liver enzymes and metabolic syndrome. Metabolism. 2003;52(9):1096-1101.

Murato T. et al. , 1969. - 89.

NewairyAA, El-SharakyAS, Badreldeen MM, Eweda SM, Sheweita SA. The hepatoprotective effects of selenium against cadmium toxicity in rats. Toxicology. 2007;242(1 -3):23-30 Epub 2007 Sep.

Nijhout HF, Reed MC, Budu P, Ulrich CM. A mathematical model of the folate cycle: new insights into folate homeostasis. J Biol Chem. 2004;279(53):55008-16.

Niro GA, Poli F, Andriulli A, Bianchi I, Bernuzzi F, Caliari L, Fontana R, Giof- freda D, Valvano MR, Podda M, Invernizzi P. TNF-alpha polymorphisms in primary biliary cirrhosis: a northern and southern Italian experience. Ann N Y Acad Sci. 2009;1173:557-563.

Nishigaki I, Hasan SH, KotakiA, Yagi K, Okuyama S. Studies on myoinositol. VII. Removal of deposited fats from dietary fatty liver. J Vitaminol (Kyoto). 1970;17(2):112-116.

Oakley F, Teoh V, Ching-A-Sue G, Bataller R, Colmenero J, Jonsson JR, Eliopoulos AG, Watson MR, Manas D, Mann DA. Angiotensin II activates I kappaB kinase phosphorylation of RelA at Ser 536 to promote myofibroblast survival and liver fibrosis. Gastroenterology. 2009;136(7):2334-2344e1 Epub 20.

OHara KA, Vaghjiani RJ, Nemec AA, Klei LR, Barchowsky A. Cr(VI)- stimulated STAT3 tyrosine phosphorylation and nuclear translocation in human airway epithelial cells requires Lck. Biochem J. 2007;402(2):261-269.

Ohishi Y, Nakamura M, Iio N, Higa S, Inayoshi M, Aiba Y, Komori A, Omagari K, Ishibashi H, Tsukamoto K. Single-nucleotide polymorphism analysis of the multidrug resistance protein 3 gene for the detection of clinical progression in Japanese patients with primary biliary cirrhosis. Hepatology. 2008;48(3):853-862.

Oliveira CP, Stefano JT, Cavaleiro AM, Zanella Fortes MA, Vieira SM, Rodrigues Lima VM, Santos TE, Santos VN, de Azevedo Salgado AL, Parise ER, FerreiraAlvesVA, CarrilhoFJ, Correa-GiannellaML. Associationofpolymorphisms of glutamate-cystein ligase and microsomal triglyceride transfer protein genes in non-alcoholic fatty liver disease. J Gastroenterol Hepatol. 2010;25(2):357-61 Epub 2009 Oc.

Ozaki I. [An experimental study on the influences of protein and Prohepar upon liver diseases.] Hokkaido Igaku Zasshi. 1961 Aug;36:394-415.

Pachkoria K, Lucena MI, Crespo E, Ruiz-Cabello F, Lopez-Ortega S, Fernandez MA, Romero-Gomez M, Madrazo A, Duran JA, de Dios AM, Borraz Y, Navarro JM, Andrade RJ. Analysis of IL-10, IL-4 and TNF-alpha polymorphisms in drug-induced liver injury (DILI) and its outcome. J Hepatol. 2008;49(1):107-14 Epub 2008 Ap.

Pari L, Murugavel P. Protective effect of alpha-lipoic acid against chloro- quine-induced hepatotoxicity in rats. J Appl Toxicol. 2004;24(1):21-26.

PastorIJ, Laso FJ, RomeroA, Gonzalez-SarmientoR. -238G&gt;Apolymorphism of tumor necrosis factor alpha gene (TNFA) is associated with alcoholic liver cirrhosis in alcoholic Spanish men. Alcohol Clin Exp Res. 2005;29( 11): 1928-1931.

Preisig R. Supplements to the editorial, Liver protection therapy// Schweiz Rundsch Med Prax. - 1970, 59(45), P. 1559-1560.

Rasbach K. [Clinical experience in the treatment of acute and chronic hepatitis as well as of compensated and decompensated liver cirrhosis with the liver hydrolysate prohepar.]. Med Monatsschr. 1955 Apr;9(4):232-6.

Rey de Vinas JL, Gonzalez-Fernandez M, Sandoval MC. Liver DNA and RNA metabolism in rats fed diets lacking methionine plus cysteine with or without restricted energy. Rev Esp Fisiol. 1995;51(3):129-138.

Ritschell W. Curative liver protection by thioctic acid.Pharm Acta Helv. (1959) 34:189-94

Romanov VS. [Use of lipoic acid and its amide in chronic liver diseases] Sov Med. 1971;34(12):43-45.

Satoh M, Matsumura T, Nakamoto M, Yamazaki M. Inhibition of TNF-trig- gering activity of lipopolysaccharide by a proteinaceous factor from normal mouse liver extract. J Immunol. 1995;155(2):877-885.

SAYRE FW, HANSEN E, STARR TJ, YARWOOD EA. Isolation and partial characterization of a growth-control factor. Nature. 1961;190:1116-1117.

Schetinger MR, Bonan CD, Morsch VM, Effects of aluminum sulfate on delta-aminolevulinate dehydratase from kidney, brain, and liver of adult mice. Braz J Med Biol Res. 1999;32(6):761-766.

Sekiya M. et al., Leber Galle Bauchspeichedruse, - 1973, - 14, - P. 582.

Shimizu M, Tanabe S, Morimatsu F, Nagao K, Yanagita T, Kato N, Nishimura T. Consumption of pork-liver protein hydrolysate reduces body fat in Otsuka Long-Evans Tokushima Fatty rats by suppressing hepatic lipogenesis. Biosci Biotechnol Biochem. 2006;70(1):112-118.

Smith AD, Kim YI, Refsum H. Is folic acid good for everyone? Am J Clin Nutr. 2008;87(3):517-533.

Sookoian S, Castano G, Gianotti TF, Polymorphisms of MRP2 (ABCC2) are associated with susceptibility to nonalcoholic fatty liver disease. J Nutr Biochem. 2009;20(10):765-70 Epub 2008 Oc.

Sookoian S, Castano GO, Burgueno AL, The nuclear receptor PXR gene variants are associated with liver injury in nonalcoholic fatty liver disease. Pharmacogenet Genomics. 2010;20(1):1 -8.

Sprince H, Parker C, Smith G; Gonzales L. Protection against Acetaldehyde Toxicity in the rat by L-cysteine, thiamin and L-2-Methylthiazolidine-4-carboxylic acid, Inflam. Res. 4 (2): 125-30, 1974.

Steger DJ, Haswell ES, Miller AL. Regulation of chromatin remodeling by inositol polyphosphates. Science. 2003;299(5603):114-6 Epub 2002 Nov.

Stern JB, Smith KA. Interleukin-2 induction of T-cell G1 progression and c- myb expression. Science. 1986;233(4760):203-206.

Stickel F, Osterreicher CH, Datz C, Ferenci P, Prediction of progression to cirrhosis by a glutathione S-transferase P1 polymorphism in subjects with hereditary hemochromatosis. Arch Intern Med. 2005;165(16):1835-1840.

Stipanuk MH. Role of the liver in regulation of body cysteine and taurine levels: a brief review. Neurochem Res. 2004;29(1):105-110.

Suitor CW, Bailey LB. Dietary folate equivalents: interpretation and application. J Am Diet Assoc. 2000;100(1):88-94.

Suriapranata IM, Sudania WM, Tjong WY, Alpha-fetoprotein gene polymorphismsandriskofHCCandcirrhosis. ClinChimActa. 2010;411(5-6):351 -8 Epub 2009 Dec.

Sziller I, Hupuczi P, Normand N, Halmos A, Papp Z, Witkin SS. Fas (TNFRSF6) gene polymorphism in pregnant women with hemolysis, elevated liver enzymes, and low platelets and in their neonates. Obstet Gynecol. 2006;107(3):582-587.

Tanaka A, Nezu S, Uegaki S, Vitamin D receptor polymorphisms are associated with increased susceptibility to primary biliary cirrhosis in Japanese and Italian populations. J Hepatol. 2009;50(6):1202-9 Epub 2009 Ma.

Tang KS, Lee CM, Teng HC, UDP-glucuronosyltransferase 1A7 polymorphisms are associated with liver cirrhosis. Biochem Biophys Res Commun. 2008;366(3):643-8 Epub 2007 Dec.

Teichert J, Hermann R, Ruus P, Plasma kinetics, metabolism, and urinary excretion of alpha-lipoic acid following oral administration in healthy volunteers. J Clin Pharmacol. 2003;43(11):1257-1267.

Toyoshima S, Watanabe F, Saido H, Accumulation of methylmalonic acid caused by vitamin B12-deficiency disrupts normal cellular metabolism in rat liver. Br J Nutr. 1996;75(6):929-938.

Trejo JL, PirizJ, Llorens-Martin MV, FernandezAM, Bolos M, LeRoith D, Nunez A, Torres-Aleman I. Central actions of liver-derived insulin-like growth factor I underlying its pro-cognitive effects. Mol Psychiatry. 2007;12(12):1118-28.

TROPEANO L, BELFIORE F. [Arginase activity in the serum of guinea pigs intoxicated with carbon tetrachloride and hepatoprotective vitamin complex.] Boll Soc Ital Biol Sper. 1959;35:1084-1086.

Turato C, Ruvoletto MG, Biasiolo A, Squamous cell carcinoma antigen- 1 (SERPINB3) polymorphism in chronic liver disease. Dig Liver Dis. 2009;41(3):212-6 Epub 2008 Jul.

Underhill J, Donaldson P, Bray G, Doherty D, Portmann B, Williams R. Susceptibility to primary biliary cirrhosis is associated with the HLA- DR8-DQB1*0402 haplotype. Hepatology. 1992;16(6):1404-1408.

Valles EG, de Castro CR, Castro JA. N-acetyl cysteine is an early but also a late preventive agent against carbon tetrachloride-induced liver necrosis. Toxicol Lett. 1994;71(1):87-95.

Veenema K, Solis C, Li R, Wang W, Maletz CV, Adequate Intake levels of choline are sufficient for preventing elevations in serum markers of liver dysfunction in Mexican American men but are not optimal for minimizing plasma total homocysteine increases after a methionine load. Am J Clin Nutr. 2008;88(3):685-692.

Vittori D, Pregi N, Perez G, Garbossa G, Nesse A. The distinct erythropoietin functions that promote cell survival and proliferation are affected by aluminum exposure through mechanisms involving erythropoietin receptor. Biochim Biophys Acta. 2005;1743(1 -2):29-36.

Wachter HP, Stille G. Protective effect of liver hydrolysate prohepar on the liver and renal injuries caused by arsenobenzols.. Naunyn Schmiedebergs Arch Exp Pathol Pharmakol. 1953;218(5):354-63.

Walker EJ, Hirschfield GM, Xu C CTLA4/ICOS gene variants and haplotypes are associated with rheumatoid arthritis and primary biliary cirrhosis in the Canadian population. Arthritis Rheum. 2009;60(4):931-937.



Wang D, Verney E, Sidransky H. Protective effect of tryptophan and cysteine against carbon tetrachloride-induced liver injury. Exp Mol Pathol. 1985;43(3):364-374.

Waterhouse P, Penninger JM, Timms E, Wakeham A, Shahinian A, Lee KP, Thompson CB, Griesser H, Mak TW. Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4. Science. 1995;270(5238):985-988.

Wickramasinghe SN. Morphology, biology and biochemistry of cobalamin- and folate-deficient bone marrow cells. Baillieres Clin Haematol. 1995;8(3):441-459.

Wojcicki J, Barcew-Wiszniowska B, Krasowska B, Rozewicka L, Samochowiec L. Hepatoprotective effect of selenium and vitamin E in rabbits fed a high-fat diet. Folia Biol (Krakow). 1991;39(1-4):37-47.

Woo CW, Prathapasinghe GA, Siow YL, O K. Hyperhomocysteinemia induces liver injury in rat: Protective effect of folic acid supplementation. Biochim Biophys Acta. 2006;1762(7):656-65.

Wood MJ, Powell LW, Ramm GA. Environmental and genetic modifiers of the progression to fibrosis and cirrhosis in hemochromatosis. Blood. 2008;111(9):4456-62

Wortham M, He L, Gyamfi M, Copple BL, Wan YJ. The transition from fatty liver to NASH associates with SAMe depletion in db/db mice fed a methionine choline-deficient diet. Dig Dis Sci. 2008;53(10):2761-74

Xu CM, Qian YL, Zhu LJ, Xian JX, Chai JR, Ruan Z, Zhang X. [Abnormal liver function associated with polymorphism of GSTT1, GSTM1 and CYP2E1 in workers exposed to N, N-dimethylformamide] Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2009;27(6):333-337.

Yan SL, Yin MC. Protective and alleviative effects from 4 cysteine-containing compounds on ethanol-induced acute liver injury through suppression of oxidation and inflammation. J Food Sci. 2007;72(7):S511-S515.

Yoneda M, Hotta K, Nozaki Y, Association between PPARGC1A polymorphisms and the occurrence of nonalcoholic fatty liver disease (NAFLD). BMC Gastroenterol. 2008;8:27.

Yoneda M, Hotta K, Nozaki Y, Endo H, Association between angiotensin II type 1 receptor polymorphisms and the occurrence of nonalcoholic fatty liver disease. Liver Int. 2009;29(7):1078-85

Zhan Q, Li YY, Nie YQ, Association of hepatic lipase gene promoter polymorphism -514C/T with nonalcoholic fatty liver disease Zhonghua Gan Zang Bing Za Zhi. 2008;16(5):375-378.

Zhang HW, Xu YT, Wang HR. [The material isolated from bovine liver promoted the immunity of chicken] Shi Yan Sheng Wu Xue Bao. 1995;28(2):111-119.

Zhou XM, Lin JS, Sun XM, Tang WX, Zhang WY, Yuan SY, Ai L. [The relationship between the plasma homocysteine level and the polymorphism of MTHFR gene C667T in liver cirrhosis] Zhonghua Gan Zang Bing Za Zhi. 2005;13(12):908-910.

<< | >>
: . ., . .. - 61 . - .: , 2012- 747 .. 2012

:

- -
- - - - - - - - - - - - - -