.. .. . : , , - .: , 1991. 496 .

.., .. /- .: -, 2003.

57 .

.., ,., .., .., .. //.. - 2009. - 6, 1.- .37.

, . .., . .,.,-1986. 196 .

.. : .// . . . - 1999; 2: .45-50.

.., .. : , 4- .- .: -, 2008. 768 .

.., ... / .:.: έ-, 2008. 947 .

.. - - - - : . ... . . , - 2000, ., 46 .

.. - ? Consilium Medicum N1/1999

. . : . - 7- ., . . - .:.: -, 2002. 664.

.. . : ,- 2001, 134 .

Acs N, Banhidy F, Horvath-Puho E, Czeizel AE. Population-based case- control study of the common cold during pregnancy and congenital abnormalities. Eur J Epidemiol. 2006;21(1):65-75.

Bao S, Knoell DL. Zinc modulates airway epithelium susceptibility to death receptor-mediated apoptosis. Am J Physiol Lung Cell Mol Physiol. 2006;290(3): L433-41 Epub 2005 N.

Bao S, Knoell DL. Zinc modulates cytokine-induced lung epithelial cell barrier permeability. Am J Physiol Lung Cell Mol Physiol. 2006;291(6):L1132-41 Epub 2006.

Belbraouet S, Biaudet H, Tebi A, Chau N, Gray-Donald K, Debry G. Serum zinc and copper status in hospitalized vs. healthy elderly subjects. J Am Coll Nutr. 2007;26(6):650-654.

Berg K, Bolt G, Andersen H, Owen TC. Zinc potentiates the antiviral action of human IFN-alpha tenfold. J Interferon Cytokine Res. 2001;21(7):471-474.

Bryant-Stephens T. Cold remedies and heart disease. J Med Assoc Ga. 1986;75(3):176-178.

Cakman I, Kirchner H, Rink L. Zinc supplementation reconstitutes the production of interferon-alpha by leukocytes from elderly persons. J Interferon Cytokine Res. 1997;17(8):469-472.

Cohen S, Alper CM, Doyle WJ, Adler N, Treanor JJ, Turner RB. Objective and subjective socioeconomic status and susceptibility to the common cold. Health Psychol. 2008;27(2):268-274.

Coto JA, Hadden EM, Sauro M, Zorn N, Hadden JW. Interleukin 1 regulates secretion of zinc-thymulin by human thymic epithelial cells and its action on T- lymphocyte proliferation and nuclear protein kinase C.

Proc Natl Acad Sci U S A. 1992;89(16):7752-7756.

Dardenne M, Savino W, Berrih S, Bach JF. A zinc-dependent epitope on the molecule of thymulin, a thymic hormone. Proc Natl Acad Sci US A. 1985;82(20):7035- 7038.

Dardenne M. Zinc and immune function. Eur J Clin Nutr. 2002;56 Suppl 3: S20-S23.

Eccles R. Acute cooling of the body surface and the common cold. Rhinol- ogy. 2002;40(3):109-114.

Fraker PJ, King LE. Reprogramming of the immune system during zinc deficiency. Annu Rev Nutr. 2004;24:277-298.

Fukamachi Y, Karasaki Y, Sugiura T, Itoh H, Abe T, Yamamura K, Higashi K. Zinc suppresses apoptosis of U937 cells induced by hydrogen peroxide through an increase of the Bcl-2/Bax ratio. Biochem Biophys Res Commun. 1998;246(2):364-369.

Garibaldi RA. Epidemiology of community-acquired respiratory tract infections in adults. Incidence, etiology, and impact. Am J Med. 1985;78(6B):32-37.

Goldmann D.A., Bacterial colonization and infection in the neonate. Am J Med 1981; 70:417-22.

Gomez NN, Ojeda MS, Gimenez MS. Lung lipid composition in zinc-deficient rats. Lipids. 2002;37(3):291-296.

Greiff L, Andersson M, Akerlund A, Wollmer P, Svensson C, Alkner U, Pers- son CG. Microvascular exudative hyperresponsiveness in human coronavirus- induced common cold. Thorax. 1994;49(2):121-127.

Haase H, Rink L. Signal transduction in monocytes: the role of zinc ions. Biometals. 2007;20(3-4):579-85 Epub 2007Ap.

HadleyAJ, Rantle CM, Buckingham JC. Thymulin stimulates corticotrophin release and cyclic nucleotide formation in the rat anterior pituitary gland. Neuro- immunomodulatio 1997;4(2):62-69.

IFCCScientificCommittee.//J. Clin. Chem. Clin. Biochem.Vol. 23-1983,hh. P.731-748.

Jarvis W.R., The epidemiology of colonization, Infection Control and Nosocomial Colonization 1996; 17:47-52.

Jennings LC, Dick EC. Transmission and control of rhinovirus colds. Eur J Epidemiol. 1987;3(4):327-335.

Kreutz RP, Tantry US, Bliden KP, Gurbel PA. Inflammatory changes during the common cold are associated with platelet activation and increased reactivity of platelets to agonists. Blood Coagul Fibrinolysis. 2007;18(8):713-718.

KurugolZ, Akilli M, Bayram N, Koturoglu G. The prophylactic and therapeutic effectiveness of zinc sulphate on common cold in children. Acta Paediatr. 2006;95(10):1175-1181.

Kurugol Z, Bayram N, Atik T. Effect of zinc sulfate on common cold in children: randomized, double blind study. Pediatr Int. 2007;49(6):842-847.

Lang C, Murgia C, Leong M, Tan LW, Perozzi G, Knight D, Ruffin R, Zalewski P. Anti-inflammatory effects of zinc and alterations in zinc transporter mRNA in mouse models of allergic inflammation. Am J Physiol Lung Cell Mol Physiol. 2007;292(2):L577-84 Epub 2006 N.

Lee T, Simon H. Dont let decongestants squeeze your heart. As many over- the-counter decongestants get a new ingredient, you might want to look for alternatives. Harv Heart Lett. 2005;16(3):3.

Lonnerdal B. Dietary factors influencing zinc absorption. J Nutr. 2000;130(5S Sup:1378S-1383S.

MacLennan C, Solomon T. Potential neurovirulence of common cold virus. Lancet. 2004;364(9448):1839-1840.

Maggini S, Wintergerst ES, Beveridge S, Hornig DH. Selected vitamins and trace elements support immune function by strengthening epithelial barriers and cellular and humoral immune responses. Br J Nutr. 2007;98 Suppl 1:S29-S35.

Maret W, Sandstead HH. Zinc requirements and the risks and benefits of zinc supplementation. J Trace Elem Med Biol. 2006;20(1):3-18 Epub 2006 Feb.

Mesner PW Jr, Bible KC, Martins LM, Kottke TJ, Srinivasula SM, Svingen PA, Chilcote TJ, Basi GS, Tung JS, Krajewski S, Reed JC, Alnemri ES, Earnshaw WC, Kaufmann SH. Characterization of caspase processing and activation in HL- 60 cell cytosol under cell-free conditions. Nucleotide requirement and inhibitor profile. J Biol Chem. 1999;274(32):22635-22645.

Moroy T, Zeng H, Jin J, Schmid KW, Carpinteiro A, Gulbins E. The zinc finger protein and transcriptional repressor Gfi1 as a regulator of the innate immune response. Immunobiology. 2008;213(3-4):341 -352 Epub 2008 J.

M^^ T, Zeng H, Jin J, Schmid KW, Carpinteiro A, Gulbins E. The zinc finger protein and transcriptional repressor Gfi1 as a regulator of the innate immune response. Immunobiology. 2008;213(3-4):341-52.

Mossad SB, Macknin ML, Medendorp SV, Mason P. Zinc gluconate lozenges for treating the common cold. A randomized, double-blind, placebo-controlled study. Ann Intern Med. 1996;125(2):81 -88.

Novick SG, Godfrey JC, Godfrey NJ, Wilder HR. How does zinc modify the common cold? Clinical observations and implications regarding mechanisms of action. Med Hypotheses. 1996;46(3):295-302.

Novick SG, Godfrey JC, Pollack RL, Wilder HR. Zinc-induced suppression of inflammation in the respiratory tract, caused by infection with human rhinovirus and other irritants. Med Hypotheses. 1997;49(4):347-357.

Overbeck S, Rink L, Haase H. Modulating the immune response by oral zinc supplementation: a single approach for multiple diseases. Arch Immunol Ther Exp (Warsz). 2008;56(1):15-30 Epub 2008 Feb.

Pelczar M.J., Chan E.C.S., Elements of microbiology 1981; 376-7.

Pernelle JJ, Creuzet C, Loeb J, Gacon G. Phosphorylation of the lymphoid cell kinase p56lck is stimulated by micromolar concentrations of Zn2+. FEBS Lett. 1991;281(1 -2):278-282.

Perry DK, Smyth MJ, Stennicke HR, Salvesen GS, Duriez P, Poirier GG, Hannun YA. Zinc is a potent inhibitor of the apoptotic protease, caspase-3. A novel target for zinc in the inhibition of apoptosis. J Biol Chem. 1997;272(30): 18530-18533.

Prasad AS, Fitzgerald JT, Bao B, Beck FW, Chandrasekar PH. Duration of symptoms and plasma cytokine levels in patients with the common cold treated with zinc acetate. A randomized, double-blind, placebo-controlled trial. Ann Intern Med. 2000;133(4):245-252.

Prasad AS, Beck FW, Bao B, Snell D, Fitzgerald JT. Duration and severity of symptoms and levels of plasma interleukin-1 receptor antagonist, soluble tumor necrosis factor receptor, and adhesion molecules in patients with common cold treated with zinc acetate. J Infect Dis. 2008;197(6):795-802.

Prasad AS. Discovery and importance of zinc in human nutrition. Fed Proc. 1984;43(13):2829-2834.

Richter M, Cantin AM, Beaulieu C, Cloutier A, Larivee P. Zinc chelators inhibit eotaxin, RANTES, and MCP-1 production in stimulated human airway epithelium and fibroblasts. Am J Physiol Lung Cell Mol Physiol. 2003;285(3):L719-29 Epub 2003 M.

Riedl SJ, Renatus M, Schwarzenbacher R, Zhou Q, Sun C, Fesik SW, Liddington RC, Salvesen GS. Structural basis for the inhibition of caspase-3 by XIAP. Cell. 2001;104(5):791 -800.

Rink L, Haase H. Zinc homeostasis and immunity. Trends Immunol. 2007;28(1):1-4 Epub 2006 Nov 2.

Saha AR, Hadden EM, Hadden JW. Zinc induces thymulin secretion from human thymic epithelial cells in vitro and augments splenocyte and thymocyte responses in vivo. Int J Immunopharmacol. 1995;17(9):729-733.

Salas M, Kirchner H. Induction of interferon-gamma in human leukocyte cultures stimulated by Zn2+. Clin Immunol Immunopathol. 1987;45( 1):139-142.

Sondergaard LG, Stoltenberg M, Doering P, Flyvbjerg A, Rungby J. Zinc ions in the endocrine and exocrine pancreas of zinc deficient rats. Histol Histo- pathol. 2006;21(6):619-625.

Stennicke HR, Salvesen GS. Biochemical characteristics of caspases-3, -6, -7, and -8. J Biol Chem. 1997;272(41):25719-25723.

Torshin I.Yu. Bioinformatics in the post-genomic era: physiology and medicine. Nova Biomedical Books, NY, USA (2007), ISBN: 1600217524, pp35-67.

Torshin I.Yu. Bioinformatics in the post-genomic era: the studies in clinical genetics. Nova Biomedical Books, NY, USA, 2008.

Truong-Tran AQ, Carter J, Ruffin RE, Zalewski PD. The role of zinc in caspase activation and apoptotic cell death. Biometals. 2001;14(3-4):315-330.

Truong-Tran AQ, Grosser D, Ruffin RE, Murgia C, Zalewski PD. Apoptosis in the normal and inflamed airway epithelium: role of zinc in epithelial protection and procaspase-3 regulation. Biochem Pharmacol. 2003;66(8):1459-1468.

Turner JM, Brodsky MH, Irving BA, Levin SD, Perlmutter RM, Littman DR. Interaction of the unique N-terminal region of tyrosine kinase p56lck with cytoplasmic domains of CD4 and CD8 is mediated by cysteine motifs. Cell. 1990;60(5):755-765.

White WB, Riotte K. Drugs for cough and cold symptoms in hypertensive patients. Am Fam Physician. 1985;31(3):183-187.

Youmans G.P., Paterson P.Y., Sommers H.M., The Biologic and Clinical Basis of Infectious Diseases, 1975.

<< | >>
: . ., . .. - 61 . - .: , 2012- 747 .. 2012


- -
- - - - - - - - - - - - - -